Line-ups: Roma v Inter
Inter use Ivan Perisic and Keita Balde Diao with Mauro Icardi, while injury-hit Roma move Alessandro Florenzi into the front four.
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The Giallorossi have huge problems to deal with, as Edin Dzeko, Stephan El Shaarawy, Lorenzo Pellegrini, Daniele De Rossi, Ante Coric and Rick Karsdorp are in the stands of the Stadio Olimpico.
Cengiz Under had a slight muscular problem in training on Saturday, but starts anyway, primarily because there are so few alternatives.
Diego Perotti and Javier Pastore are back in the squad after lengthy lay-offs, but Eusebio Di Francesco confirmed they are in no condition to start.
The versatile Florenzi is pushed up into the supporting trio behind Patrik Schick, joining Under and Nicolò Zaniolo, who left Inter over the summer as part of the Nainggolan deal.
Federico Fazio is not even on the bench due to an ankle injury.
Inter have Sime Vrsaljko back, although he is not risked from the start, while Radja Nainggolan is out with a muscular and ankle issue, so won’t face his former teammates.
Joao Mario and Borja Valero were expected to challenge for one place, but instead it’s Matias Vecino who drops to the bench, with the Portuguese midfielder moved into the more advanced trequartista role.
Perisic and Keita Balde Diao flank Mauro Icardi, leaving Matteo Politano out.
Roma: Olsen; Santon, Manolas, Juan Jesus, Kolarov; Cristante, Nzonzi; Florenzi, Zaniolo, Under; Schick
Roma bench: Mirante, Fuzato, Luca Pellegrini, Perotti, Marcano, Pastore, Kluivert, Riccardi, Celar
Inter: Handanovic; D’Ambrosio, De Vrij, Skriniar, Asamoah; Borja Valero, Brozovic; Keita, Joao Mario, Perisic; Icardi
Inter bench: Padelli, Vrsaljko, Gagliardini, Vecino, Lautaro Martinez, Ranocchia, Politano, Miranda, Candreva
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